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CD 52 Level


CD52 is a protein that contains sugar and is usually found on the surface of most immunological cells from which it can be shed to subsequently re-appear in a soluble form in blood. High levels are normally associated with an increase in the rate of producing immunological cells whilst low levels suggest a lack of immunological cells.


CD52, also known as the CAMPATH-1 Antigen, is a transmembrane glycoprotein which is highly expressed on the immunological cells, e.g. virtually all lymphocytes, macrophages, monocytes and eosinophils. CD52 can be shed from the cell surface and appears in the blood in a soluble form. This assay is designed to evaluate the general state of the activity of the Immune System.

High levels of cellular CD52 are associated with increased production of immunological cells and, in all probability, their active status. Low levels of cellular CD52 indicate the depletion of the immunological cells, their lack of production or, in all probability, a non-active status. High levels of soluble CD52 indicate, in all probability, the non-active status of immunological cells that have lost their CD52 or are undergoing destruction.


This assay will provide extremely valuable and accurate information relating to the following pathological conditions :-

- All forms of cancer and immuno-deficiency.
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