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Alpha Fetoprotein (AFP)
Gene Expression


Alpha Fetoprotein is normally present at birth but very quickly diminishes to a very low level. In many types of cancer AFP production is known to increase, particularly when a primary hepato-cellular carcinoma has formed, and often results in an increase in the number of cancerous cells present. Hence high quantities of AFP are associated with an accumulation of Cancer Cells whereas low quantities indicate that there is unlikely to be any proliferation.


AFP is normally present in the tissues and plasma of the foetus and its concentration falls very rapidly after birth. In adults AFP is produced in very low quantities in the liver. However, AFP production can be significantly increased in many types of cancer, especially primary hepatocellular carcinoma. In some cases a moderate increase may be temporary and associated with the tissue’s (usually the liver’s) response to injury. This assay is designed to evaluate the presence of the proliferating cells, i.e. Cancer Cells and cells, in any injured tissue with an active regeneration process.

High AFP quantities are associated with an accumulation of Cancer Cells and, in some cases, with an active regenerative process in injured tissue. Low quantities indicate the absence of the proliferation of some types of Cancer Cells.


This assay will provide extremely valuable and accurate information relating to all forms of cancer.


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