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p53 is a suppressor gene which promotes the self-destruction of an abnormal (e.g. transformed, infected) cell. This assay is able to obtain information relating to the state of activity of the first line of defence against the transformation of normal cells to cancerous cells.

A high quantity indicates that there is the possibility to destroy any Abnormal Cells due to the presence of an active p53 gene. Conversely, a low quantity indicates that there is self-resistance of Abnormal Cells to be destroyed.


p53 is a tumour suppressor gene which plays a critical role in the body’s defence system against cancer. It initiates the repair of cells damaged by DNA and, in cases where the DNA cannot be repaired, activates self-destruction of these impaired (pre-cancerous or infected) cells. In this way, p53 protects genetic stability, both minimising the number of cells that become cancerous and preventing the uncontrolled replication of such cells if they do arise.

The p53 assay provides an insight into the status of this first line of anti-cancer defence. High quantities indicate the active functioning of p53 and thus the potential to effectively destroy any Abnormal Cells. Conversely, reduced levels of the gene suggest that these impaired cells have developed a self-resistance to p53-induced elimination, with an increase in the risk for cancer development.


This assay will provide extremely valuable and accurate information relating to all forms of cancer.
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